The G-BA has specified the drug combination of a calcium channel blocker (amlodipine or nitrendipine) and an ACE inhibitor (lisinopril, ramipril or enalapril) as the appropriate comparator therapy.

A renin-angiotensin system combination polypill to treat high BP was associated with improved adherence and lower all-cause ... ramipril/amlodipine polypill vs. multiple pills (IRR = 0.526 ...

June 30, 2008 Recorded April 1, 2008 in Chicago New data from the Avoiding Cardiovascular Events in Combination Therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial were ...

Moreover, although treatment with ramipril was significantly better than amlodipine it was not better than metoprolol in the mean chronic GFR slopes in patients with a baseline UP/Cr >0.22 (300 mg ...

The primary outcome (death from cardiovascular causes, MI, stroke, or hospitalization for HF) occurred in 1,412 patients in the rampiril cohort (16.5%), compared with 1,423 in the telmisartan ...

Combination therapy with up to 3 antihypertensive medications in a single pill decreases risk for cardiovascular events and all-cause mortality.

Aliskiren 150–300 mg per day or ramipril 5–10 mg per day for was administered for 12 weeks with optional add-on therapy of hydrochlorothiazide (12.5–25 mg per day) at week 12 and amlodipine ...

A combination of ramipril (Altace) 10 mg daily plus telmisartan (Micardis) 80 mg daily does not reduce mortality or cardiovascular morbidity compared with ramipril alone, based on a randomized ...

Combination therapy using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers reduces the levels of excess protein in the urine (proteinuria) more than either therapy alone ...

Mean blood pressure was lower in both the telmisartan group (a 0.9/0.6 mm Hg greater reduction) and the combination-therapy group (a 2.4/1.4 mm Hg greater reduction) than in the ramipril group.