Abstracts are available on the EASL Congress 2025 website at https://www.easlcongress.eu/. The posters are expected to be ...

and that the distribution of activated G proteins probably reflects the shallow gradient of receptor occupancy rather than the sharply localized physiological response at the leading edge of the cell.

full receptor occupancy, and lack of DR3 agonism. Our encouraging preclinical data underscore SL-325’s potential for DR3 blockade to provide potentially best-in-class clinical remission rates ...

TMP-301 has been evaluated in over 80 healthy volunteers in the Phase 1 setting with an acceptable safety and tolerability profile and has demonstrated robust receptor occupancy via positron ...

Shattuck made the difficult but appropriate decision to terminate our SL-172154 program in 2024, and rapidly transitioned to our potential ...

full receptor occupancy, lack of DR3 agonism – – SL-325 advances toward Phase 1; on track for IND filing in the third quarter of 2025 – – Cash balance of approximately $73.0 million as of ...