In prokaryotes, the small subunit is known as the 30S subunit, and the large subunit is the 50S subunit. Each subunit consists of ribosomal RNA (rRNA) and ribosomal proteins. The rRNA forms the ...

Bacterial ribosomes, the subject of most engineering efforts, are smaller than ribosomes in eukaryotes. Their large subunit incorporates two rRNAs—23S and 5S—and the small subunit has just one ...

Maturation of the ribosome is a complex operation. Work now shows that the 90S precursor of the small 40S subunit undergoes a 'molting' process, during which it progressively discards its ...

Namely, the large subunit of the ribosome has to be detached again from the protein-conducting channel. ... a small wedge, the protein UFM1, at the large subunit," explains Becker.

Maturation of the ribosome is a complex operation. Work by an Ludwig-Maximilians-Universitaet (LMU) in Munich team now shows that the 90S precursor of the small 40S subunit undergoes a 'molting ...

Apparently, ribosomal proteins of the small subunit were more likely to be retained than the large subunit proteins, and most frequently lost proteins were located on the ribosome surface, where ...

More information: Natalia Khalatyan et al, Ribosome customization and functional diversification among P-stalk proteins regulate late poxvirus protein synthesis, Cell Reports (2025). DOI: 10.1016 ...

Inserting self-splicing introns enabled gene editing at multiple locations simultaneously in orthogonal ribosomes, the messenger RNA binding site (green) in the small subunit (beige) and the ...

At the beginning of the 1950s, scientists realized that ribosomes, large complexes of RNA and protein, ... In 1980, she generated the first three-dimensional crystals of the ribosome's large subunit.

Model of the large subunit of the mitochondrial ribosome (Graphics: Group Prof. Nenad Ban / ETH Zurich) The ribosome can be thought of as a decryption device housed within the cell. It is able to ...