Like so many organisms on the planet, when cells experience mosh-pit-level crowding, they may just become stressed. Yet unlike most other life forms, cells subject to physical stress from crowding ...

Epithelial tissue crowding, or the accumulation of too many epithelial cells in a single tissue, can result in cell extrusion, an irreversible process in which the tissue gets rid of cells to help ...

Epithelial cells can relieve tissue crowding through apical macropinocytosis, a process that reduces cell surface area by internalizing extracellular material, thereby minimizing the need for ...