Spliceosome Structure And Function; ... The spliceosome is a dynamic macromolecular machine responsible for the precise excision of introns from pre-messenger RNA (pre-mRNA), ...

In this new study, the researchers reveal the structure of U11 snRNP – one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...

In this new study, the researchers reveal the structure of U11 snRNP -- one of the five subunits of the minor spliceosome, which initiates the intron selection process. Stitching gene pieces together ...

Researchers at the Centre for Genomic Regulation (CRG) in Barcelona have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology.

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing ...

Image: “Like a constellation of atoms” – splicing modulator (purple) bound to a spliceosome subunit. Credit: Professor Vlad Pena. Scientists have uncovered the inner workings of one of the most ...

Researchers have created the first blueprint of the human spliceosome, the most complex and intricate molecular machine in human biology. The vast majority of human genes -- more than nine in ten ...