Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research. Obesity leads to changes in the splicing pattern of ...

RNA splicing is a cellular process that is critical for gene expression. After genes are copied from DNA into messenger RNA, portions of the RNA that don't code for proteins, called introns, are ...

These types of AS events occur when two or more splice sites are recognized at one end of an exon. Alternative 3′ SS and 5′ SS selection account for 18.4% and 7.9% of all AS events in higher ...

The company used whole exome and RNA sequencing to analyze 10,000 patient samples across 33 tumor types. The analysis looked at more than 400 splicing factors, turning up 199 genes with putative ...

Alternate 5’ or 3’ splicing: Alternative splicing can also be mediated by the joining of exons at alternative 5’ or 3’ splice sites. Intron retention: This type happens when non-coding portions of a ...

PAML is a type of leukemia in which the bone marrow makes a large number of abnormal blood cells. In healthy children, bone marrow makes blood stem cells that become different types of mature ...

Not only is splicing cell-type-specific, but its genetic regulation is also cell-type-specific. Terminologically, an sQTL is a genetic variant that influences the splicing of RNA transcript.

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to ...