Often, before data are even collected, it is necessary to calculate and justify the required sample size for a study. Choosing an appropriate sample size is important since it allows us to detect ...

Often, before data are even collected, it is necessary to calculate and justify the required sample size for a study. Choosing an appropriate sample size is important since it allows us to detect ...

Xiaofeng Liu, Statistical Power and Optimum Sample Allocation Ratio for Treatment and Control Having Unequal Costs Per Unit of Randomization, Journal of Educational and Behavioral Statistics, Vol. 28, ...

The primary objective of a phase I dose-finding trial is to identify the maximum tolerated dose (MTD) of an experimental drug. MTD is typically defined as the highest dose where the probability of the ...