CD4+ conventional T (Tconv) cells, or helper T cells, inspect the peptides presented by dendritic cells. If the peptides are foreign antigens, the T cells expand in numbers and transform into an ...

Previous studies have identified TIM3 (T-cell immunoglobulin domain and mucin domain 3) as a negative regulator of T helper 1 (T H 1 ... In a mouse model of multiple sclerosis, the expression ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper ...

The researchers of the present study used Apc min/+ mice, a mouse model for intestinal ... antigens. T-cells within the small intestine lamina propria, particularly T helper 1 (Th1) cells, prevent ...

A study shows that the semi-synthetic bile acid NorUDCA inhibits in the intestine the formation of pro-inflammatory T helper 17 cells ... in a humanized mouse model with cells from PSC patients ...