This system incorporates a two-step T cell activation process that allows for highly precise tumor targeting and a controlled immune activation. Using the firearm analogy, Revitope opted to apply ...

Macrophages interact with T cells in order to bring about T cell activation in target organs ... so research in this project aims to reveal the details of this inflammatory process, with the long term ...

A pivotal study 1 in 2011 used second-generation CAR T cells to achieve sustained T cell activation and remission ... It’s a simple process, with minimal off-target effects, and works on a ...

The researchers engineered cancer cells to re-express Parkin and found that Parkin contributes to the production of interferons, which activate and attract T cells to fight the tumor. The findings ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

Ten years of substantial work by Université de Montréal immunologist Nathalie Labrecque's team at the Montreal Clinical ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...

Our blood consists of many cell types that develop through different stages from a precursor type -- the blood stem cell. An international research team has now investigated the developmental pathways ...

A groundbreaking study published in Research (2025, DOI: 10.34133/research.0545) has elucidated the molecular mechanisms by which protein phosphatase 2A (PP2A) regulates CD8+ T cell-mediated immune ...