A Northeastern University researcher has identified a way to target two of the deadliest cancer types, melanoma and triple ...

Drug-delivering aptamers that can precisely target leukemia stem cells with enhanced potency have been developed. Delivering anticancer drugs with specificity and potency to cancer stem cells is an ...

These small messengers could be a key to developing new cancer-fighting drugs and therapies, but it has been unclear how exactly the recipient cells absorb the extracellular vesicles and their ...

In part 1 of our interview with Leland Metheny, MD, he explained how a new triple-target chimeric antigen receptor (CAR) T-cell therapy works in multiple myeloma.

Programming cells to target brain tumors Scientists have developed CAR-T cells capable of targeting malignant gliomas while preserving healthy tissue Date: September 26, 2024 Source: Université ...

Using single-cell RNA sequencing of murine macrophages, a distinct and highly susceptible Kupffer cell subtype, Clec4F + /CD206 +, emerged, with heme oxygenase 1 (HMOX-1) playing a pivotal role.

mRNA to make a customized cell Most CAR-T cells are generated using viral vectors, a technique that has proved its worth in certain diseases but is not very suitable in the brain.

Drug-delivering aptamers target leukemia stem cells for one-two knockout punch Date: April 3, 2025 Source: University of Illinois at Urbana-Champaign, News Bureau Summary: Drug-carrying DNA ...