Here, using HDM challenged mice and developing an in vitro pTh2 culture system, the authors investigate the function ... Th1-dominant TME via regulation of glutamine catabolism and triggers a Th1 ...

but it also helps to ensure their function and longevity by giving them the traits of both Th1 (effector) and Th17 (stemness) cells. Th1 cells can mount an anti-cancer response but are short-lived ...

With age, the normally tight orchestration of interdependent immune functions ... DCs and T-cell initiates, through release of specific cytokines (as described above), destructive Th1 or Th2 ...