but it also helps to ensure their function and longevity by giving them the traits of both Th1 (effector) and Th17 (stemness) cells. Th1 cells can mount an anti-cancer response but are short-lived ...

With age, the normally tight orchestration of interdependent immune functions ... DCs and T-cell initiates, through release of specific cytokines (as described above), destructive Th1 or Th2 ...

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...