Hosted on MSN2mon
Cell death types and their relations to host immune pathways
A new review was published as the cover paper of Aging, titled "Types of cell death and their relations to host immunological pathways." Various immune pathways in the host, such as TH1 ...
News-Medical.Net on MSN1d
How your skin’s microbes shape immunity, inflammation, and chronic skin disease
Skin microbes do more than coexist—they shape immune responses, repair tissue, and influence gene expression across your ...
Medscape2d
Effects of Menopause on Autoimmune Diseases
Improper self-antigen recognition by DCs and T-cell initiates ... are known to drive physiological selection of Th1 or Th2 pathways. A perturbation in immune receptor signaling may underlie ...
Scientific Research Publishing6mon
Research Progress of T-Cell Immunoglobulin and Mucin Domain-Containing Protein-3 (Tim-3) in Respiratory Diseases ()
In conclusion, Tim-3 was characterized as a novel immune checkpoint molecule with pathophysiological significance in respiratory oncology. Its stage-dependent expression dynamics and multimodal ...
Nature1mon
Regulatory T-cell development: is Foxp3 the decider?
Thus, understanding differentiation pathways and functional attributes ... that could skew differentiation toward Th2 phenotype instead of Treg cells. Foxp3 can boost Treg metabolic and ...
Nature4mon
The KDDF immunology pipeline: translating cutting-edge science into novel therapeutics
ATB1606 suppresses an excessive Th2 response to TSLP secreted by keratinocytes, as well as dampening activation of tissue-resident memory T cells and ... the Keap1/Nrf2 pathway by selectively ...