A fed-batch reaction is harder to design than a batch process because of the need to specify all the variables and quantities.

“With detailed process comprehension of the IVT fundamentals, the conditions for the operation of continuous in vitro transcription could be optimized in this work to produce 55% more mRNA with ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

How a flexible protein domain links gene transcription and RNA processing. University of Freiburg. Journal Cell Reports DOI 10.1016/j.celrep.2025.115616 ...

We will also showcase our advanced in vitro transcription (IVT) production techniques and our novel circular RNA chromatography purification process, which consistently elevates circRNA purity levels ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...