How a flexible protein domain links gene transcription and RNA processing. University of Freiburg. Journal Cell Reports DOI 10.1016/j.celrep.2025.115616 ...

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

A new study led by Stephen D. Nimer, M.D., director of Sylvester Comprehensive Cancer Center, part of the University of Miami ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that causes progressive muscle weakness. A research ...

“With detailed process comprehension of the IVT fundamentals, the conditions for the operation of continuous in vitro transcription could be optimized in this work to produce 55% more mRNA with ...

We will also showcase our advanced in vitro transcription (IVT) production techniques and our novel circular RNA chromatography purification process, which consistently elevates circRNA purity levels ...

RNA transcription isn’t a fully continuous process; instead it often occurs in short bursts where, at one moment, a gene may be highly expressed, but at another time, that gene may not be ...

How does a cell know when it’s been damaged? A molecular alarm, set off by mutated RNA and colliding ribosomes, signals ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology work with RNA origami. This tool uses the multifunctionality of the natural ...