Around 2 m (six and a half feet) of DNA that make up the human genome are contained within a nucleus that is only 10 micrometers in diameter, which is 100,000 times smaller than the DNA's length.

With this in mind, Zidovska and her colleagues focused on RNA polymerase II—responsible for the transcription and one of the most abundant molecular motors in the cell nucleus.

Understanding the mechanics behind transcription-dependent motions of single genes in the nucleus might be critical for understanding the human genome in health and disease." ...

Understanding the mechanics behind transcription-dependent motions of single genes in the nucleus might be critical for understanding the human genome in health and disease.” ...

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

With this in mind, Zidovska and her colleagues focused on RNA polymerase II—responsible for the transcription and one of the most abundant molecular motors in the cell nucleus.

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

In addition to exporting materials out of the nucleus, the protein, called Exportin-1 (also called Xpo1 or Crm1), seems to play a role in promoting gene transcription, the process that creates RNA ...

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Transcription-dependent mobility of single genes and genome-wide motions in live human cells. Nature Communications , 2024; 15 (1) DOI: 10.1038/s41467-024-51149-4 Cite This Page : ...