The binding of proteins to DNA is crucial for producing other proteins, ensuring that all the necessary processes in cells are performed, and for switching genes on or off. Proteins that bind to DNA ...

A new physiological salt-based method enables high-resolution transcription factor mapping in small and single-cell samples.

Improved understanding of how bacterial defense mechanisms operate may help scientists select phages with the best chance of ...

The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription, and answer long-standing questions about the initiation mechanism and ...

Transcription factors are proteins that bind to specific DNA sequences to control gene expression, guiding cells to become specific types—such as skin, muscle, or placenta cells.