High iron levels can promote oxidative stress by producing reactive oxygen species (ROS), which induce damage to both cells ...

Researchers have found in a new study that in patients with heart failure and iron deficiency, ferric carboxymaltose did not ...

Semin Liver Dis. 2005;25(4):381-391. In a population study of 3011 subjects, 192 were found to have a transferrin saturation of ≥ 45%, but when followed over 4 years, only 35 had persistent ...

Post hoc results support the initiation of SGLT2 inhibitors in patients with diabetic nephropathy regardless of iron deficiency. Canagliflozin treatment may improve iron markers and hemoglobin levels ...

The third primary endpoint, CV death or first HF hospitalization in the subset of patients with a transferrin saturation < 20%, occurred in 18.9% and 25.6%, respectively (P = 0.07). Thirty-four ...

placebo for adults with HF and iron deficiency. Results were similar for those with transferrin saturation less than 20%. CHICAGO — Ferric carboxymaltose, an IV iron replacement therapy ...

ferric carboxymaltose did not significantly reduce the time to first heart failure hospitalization or cardiovascular death in the overall cohort or in patients with a transferrin saturation less ...

Main Outcome Measures: Iron deficiency anemia and ID were determined by levels of hemoglobin, serum iron, total iron-binding capacity, transferrin saturation, and serum ferritin. Conclusions ...