HCC is particularly adept at manipulating the TIME via exosome-mediated mechanisms. These vesicles reprogram immune and stromal cells, creating an environment conducive to tumor growth.

A new study has uncovered an unexpected way cancer cells can escape the immune system, making it harder for treatments to work. The study explains how a type of cancer cell death can actually make ...

In order to survive, cancer cells need to evade this surveillance. Now a new study by researchers at the Netherlands Cancer Institute reveals a new way cancer cells escape the immune system.

By identifying mitochondrial transfer as a novel immune evasion mechanism, this study opens new possibilities for improving cancer treatment. Blocking mitochondrial transfer could enhance ...

Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells. However, many cancers can escape immune surveillance through various mechanisms, resulting in ...

Since cholesterol depletion primarily triggers necrosis, this approach may also enhance the immune system's ability to recognize and attack the remaining cancer cells.

New mechanism: How cancer cells escape the immune system. Goethe University Frankfurt. Journal Cell DOI 10.1016/j.cell.2024.09.048. Keywords /Health and medicine/Diseases and disorders/ Cancer ...

The tumor immune microenvironment (TIME) ... These interactions drive critical aspects of tumor development, including immune escape, angiogenesis, drug resistance, and metastasis.

The team designed a unique trispecific antibody encoded in a DNA-encoded delivery mechanism. Their DNA-encoded trispecifics, named "DTriTEs," linked cancer-killing T cells through the CD3 protein ...

Since cholesterol depletion primarily triggers necrosis, this approach may also enhance the immune system's ability to recognize and attack the remaining cancer cells.