All two-hybrid screening systems rely on the fact that transcriptional activation and DNA-binding domains of transcription factors are modular in nature 6,7. In these systems, the coding sequence ...

The AntibodyArray is a membrane on which antibodies to a variety of protein ligands are immobilized. Users of the technology apply a cell lysate to the array and incubate to allow proteins to bind to ...

The identification of protein interactions has been greatly simplified by the invention of yeast-based screening assays such as the yeast two-hybrid system. However, yeast two-hybrid assays cannot ...