This mammalian homologue of the yeast protein Sec1 binds directly and tightly to the t-SNARE on the presynaptic plasma membrane, syntaxin-1A; moreover, binding of n-Sec1 to syntaxin-1A blocks v ...
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Researchers highlight role 'workhorse protein' plays in keeping nervous system running smoothly"I work on a specific protein called SNAP-25," says Bhasne. "Without SNAP-25, the SNARE complex, which is responsible for guiding the synaptic vesicle to the right docking points on the ...
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