Nucleophilic substitution reactions remain a cornerstone of organic chemistry, offering a window into the fundamental aspects of reactivity and selectivity in molecular transformations.

The transition state of a nucleophilic aromatic substitution reaction has always been presumed to be a σ complex. However, the transitory nature of such species has meant that they have so far ...

But one reaction, known as the nucleophilic vinylic substitution or SNV reaction, which could allow chemists to build even more complex structures, has been less studied because it's notoriously ...

But one reaction, known as the nucleophilic vinylic substitution or SNV reaction, which could allow chemists to build even more complex structures, has been less studied because it's notoriously ...