The Structure and Function of the Nephron. Each kidney contains approximately 1,000,000 nephrons, which are comprised of a section called the renal corpuscle and the renal tubule.

More information: Louis S. Prahl et al, Jamming of nephron-forming niches in the developing mouse kidney creates cyclical mechanical stresses, Nature Materials (2024). DOI: 10.1038/s41563-024-02019-3 ...

The human kidney is a masterclass in biological engineering. Responsible for filtering approximately 50 gallons of blood ...

Mouse kidney nephron progenitor cells (purple) forming the developing nephron tubules (yellow) of the kidney’s filtering units, the nephrons. (Image by Helena Bugacov/McMahon Lab) ...

COVID-19-associated nephropathy includes tubular necrosis and capillary congestion, with evidence of SARS-CoV-2 in various segments of the nephron, investigators reported in Kidney 360.. A team ...

GFR, the product of the number of nephrons and the average single-nephron GFR, is generally considered the best overall index of kidney function in health and disease. 9 The nephron number ...

Developing kidneys from scratch. University of Pennsylvania School of Engineering and Applied Science. Journal Nature Materials Funder U.S. National Science Foundation, NIH/Eunice Kennedy Shriver ...

Early diagnosis of chronic kidney disease (CKD) is key to managing progression of the disease. A new technique analyzing urine extracellular vesicles (uEVs) -- cell-derived nanoscale spherical ...