The idea was to isolate a ribozyme that bound an activated amino acid, react the amino acid with the 5'-OH of the ribozyme, and then catalyze transfer of the activated amino acid to a designated tRNA.

All living organisms encode the amino acid sequences of proteins as nucleotide sequences (genetic information) in their ...

When the tRNA’s southern tip, called its anticodon, pairs with the corresponding codon on mRNA, the tRNA’s panhandle transfers an amino acid to the ribosome.

Keywords protein synthesis, amino acids, mRNA, ribosome, tRNA, initiation factors, dynamic interactions, translation, genetic instructions Email us at [email protected] if you have questions ...

One type of ribonucleic acid (RNA) called transfer RNA (tRNA) ferries amino acids, the building blocks of proteins, to molecular machines known as ribosomes. Therefore, researchers have known that ...

In a new study, researchers explain how tRNA-like components act as scaffolds for peptide bond formation between amino acid–bound “RNA minihelices,” which are half tRNA-like molecules ...

The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have ...

During tRNA development, the researchers identified 12 highly active tRNA synthetase/tRNA pairs in Escherichia coli that can add canonical and noncanonical amino acids. Then, Badran’s team used ...

Neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, are devastating and incurable diseases.

Cells contain helper molecules called transfer RNAs (tRNAs), which carry building blocks (amino acids) to make proteins.