In a healthy individual, T cells find cancer cells and release the protein interferon-gamma, a potent cytokine that stops tumor growth. However, interferon-gamma has limited effects on directly ...

how HIF1α in T cells is key for induction of interferon gamma, or IFN-γ, in that hypoxic environment. The cytokine IFN-γ is known to be essential to induce the tumor-killing capacity of T cells.

As the tumors grew, the researchers observed fewer T cells and a reduction in cytokine levels ... an organ with a large population of CTLs—they found that CTLs exhibited enhanced interferon gamma ...

T cells are white blood cells that are major players in the ... “That benefit of exercise training is dependent on Treg, because they’re controlling interferon-gamma production,” said Mathis. Ablation ...

A significant discovery has identified a missing "gatekeeper" protein as the root cause of dry mouth in Sjögren's syndrome — a finding that could change the way the disease is treated.

C57BL/6 mice deficient in interleukin12 or gamma interferon showed faster acute vascular rejection than did wild-type mice. Furthermore, mice defective in B-cell development showed no acute ...