In the early days of President Donald Trump's second term, Alaska Sen. Lisa Murkowski has openly challenged or rebuked him at least three times — stunning for a congressional Republican who has faced his wrath before and yet remains unbowed by pressure to embrace his agenda.

Lisa Murkowski, a frequent thorn in the U.S. president’s side, says the Arctic island is “open for business, but not for sale.”

Moderate GOP Sen. Lisa Murkowski of Alaska has broken her silence, saying she won't be voting to confirm Pete Hegseth as secretary of defense.

A defining duo of the first Donald Trump administration is back.

President Donald Trump said Friday that he wasn't expecting Republican Sens. Lisa Murkowski (Alaska) and Susan Collins (Maine) to vote against his controversial nominee for secretary of Defense, Army veteran and former Fox News host Pete Hegseth.

We shouldn’t expect McConnell to be the next John McCain or Mitt Romney, but his vote Friday against Pete Hegseth previewed some fascinating dynamics ahead.

Republican Alaska Sen. Lisa Murkowski joined with a foreign lawmaker on Monday to dismiss President Donald Trump’s quest to acquire Greenland, saying in a joint statement that the Danish ...

The President's order to rename Denali, North America's highest peak, back to Mount McKinley does not agree with Alaska senator.

President Donald Trump has kicked off his second term with a flurry of executive actions on immigration, the economy, DEI and more.

Lisa Murkowski, the senior United States senator from Alaska, has held the seat since 2002. When will she be up for re-election? Here's what we know.

Sen. Lisa Murkowski is opposing the nomination of Pete Hegseth to be President Donald Trump's Defense secretary.

U.S. Sen Lisa Murkowski was alone in stridently opposing Trump’s blanket pardon for Jan. 6 defendants, and his order to rename Denali as Mount McKinley.