The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

At a transcriptional level, ecubectedin induced significant downregulation of key NE regulators, including ASCL1, NEUROD1, POU3F2, MYCN, EZH2 and SOX2, in both NEPC and NE-SCLC. In CP-IBI-034 tumor ...

Results on both human and mouse ATRTs reveals that ATRTs resemble two distinct developmental trajectories: one resembling a gradient of neuronal differentiation from neuroepithelial (NES, SOX2, OTX2) ...

Center for Clinical Pharmacy, Cancer Center, Department of Pharmacy, Zhejiang Provincial People’s Hospital, Affiliated People’s Hospital, Hangzhou Medical College, Shangtang Road No. 158, Hangzhou ...