Fatty acid amide hydrolase (FAAH) is a promising therapeutic target for the treatment of pain and CNS disorders. However, the development of potent and safe FAAH inhibitors is hindered by their ...

A decrease in fatty acid amide hydrolase (FAAH) activity increases the levels of endogenous analogues of cannabinoids, or endocannabinoids. 1 FAAH inhibitors have shown analgesic and ...

image: Optimized reaction conditions for amide bond formation in nitrogen-containing heterocyclic compounds using carboxylic acid requires only 4-(N,N-dimethylamino)pyridine N-oxide (DMAPO) and di ...

Fatty acid amide hydrolase is an enzyme responsible for anandamide degradation, thus determining the bioavailability and functions of this endogenous ligand of cannabinoid receptors.

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS ...