N-terminal acetylation dysregulation in the heart causes severe arrhythmia and cardiomyopathy. The authors show that stem cell models demonstrate ion channel trafficking defects and sarcomeric ...

The Factors Behind the Shifting Trends of Ischemic Heart Disease and Stroke Nov ... levels of methylmalonic acid and the weakening of CD8+ T cells, shedding light on potential pathways through ...

[29] Cao, Gollapudi, Sharman, Jia, and Gupta (2010) Age-related alterations of gene expression patterns in human CD8+ T ... Heart Circ Physiol, 6, H2698-704. [71] Chiarugi and Giannoni (2008) Anoikis: ...

A key enzyme and its molecular pathway are critical to keeping certain immune cells active and away from "exhaustion," ...

WEHI scientists have uncovered a promising new way to enhance the effectiveness of vaccines by tapping into the potential of a specific type of immune cell, opening the door to long-lasting vaccines ...

A new gene therapy reversed heart failure in pigs by repairing heart function through cBIN1, showing major promise for future ...

These heart cells rupture and leak DNA, which sparks a damaging immune response. This breakthrough challenges long-held ...

22% of CD8+ T-cells are located in stroma areas (outlined in green). Distance of tumor cells from blood vessels The same morphological differentiation capabilities can also be used on ...

Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...

Lipitor is a reasonable choice for the prevention of heart attack and stroke in a person at an increased risk, such as a 64-year-old man with a coronary calcium score of 184. (I can't give a ...

When they first broke up, they hit the bar scene in earnest with their best pals, but their heart just wasn't in it, no matter how many Jolly Rancher shots they plied themselves with. But just the ...