Biopsy also may be useful in predicting the prognosis, especially indicating the possible evolution of chronic cholestasis. Biochemical evidence of improvement after drug withdrawal is ...

Giloy, a popular herb in Ayurvedic medicine, gained prominence during the COVID-19 pandemic for its immunity-boosting ...

Ipsen’s elafibranor has shown promise as a treatment for primary sclerosing cholangitis (PSC), a rare liver disease that ...

Liver fibrosis is known to be the main driver of chronic liver disease as well ... “Physiological factors such as hepatic inflammation, cholestasis, and vascular congestion may [also] alter ...

AIH is a chronic and progressive inflammation of the liver of unknown etiology. PBC is also a disease affecting the liver in which the immune system mistakenly attacks the intrahepatic bile ducts ...

Under pathophysiological conditions, such as cholestasis, bile-acid transporters exert crucial adaptive functions to minimize the deleterious effects of bile-acid accumulation. Important ...

It is already approved in the EU under that name for progressive familial intrahepatic cholestasis (PFIC), another ... unable to tolerate UDCA. PBC is a chronic, autoimmune disease in which ...

PBC is a chronic, autoimmune disease in which bile ... and progressive familial intrahepatic cholestasis (PFIC). Ipsen is currently not running studies of odevixibat in PBC, but has a phase ...

White patients had an increased burden of advanced liver fibrosis vs Black patients, despite comparable levels of inflammation.

Pancreatic dysfunction occurs secondary to fibrosis and leads to chronic diarrhea, malabsorption ... including renal tubulopathy, liver cholestasis and/or fibrosis, adrenal insufficiency, diabetes ...

Maternal conditions such as gestational diabetes, preeclampsia, and intrahepatic cholestasis of pregnancy are also concerning. “Chronic conditions like hypertension or even infections during pregnancy ...