Praziquantel (PZQ) is widely used to treat schistosomiasis. However, this chiral active pharmaceutical ingredient (API) is still produced as a racemic compound while only the (R)-enantiomer is active.

To uniform Ag layer, citric acid was added. Citric acid suppresses the Cu dissolution and stabilize the Cu surface. The morphologies of Ag layer were observed by scanning electron microscopy (SEM).

Following acid treatment, the samples were neutralized with Tris buffer (0.2 M, pH 8.0) and subjected another cycle of IA enrichment, and recovery was evaluated by comparing the TR4495 levels in the ...