Lipid nanoparticles (LNPs) as gene delivery vectors have revolutionized the therapeutic paradigm in mRNA therapy. The pH-dependent lipid components can prevent endosomal retention of mRNA and promote ...

In patients with small intestinal Crohn’s disease (CD), there is a need for a simple, non-invasive test to reduce dependence on invasive procedures (eg, enteroscopy) and costly imaging (eg, MRI or CT ...