They then introduced the desired cytokine molecule engineered with a compatible DBCO chemical group so that it attached to the T cell via the sugar. Having assessed the effectiveness of the attachment ...

Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

Discovering that a seemingly innocuous fatty molecule on the surface of the "strep throat" bacterium S. pyogenes can actually activate the immune system to release inflammatory cytokines ...

Partially blocking a receptor that helps regulate the activity of the inflammatory cytokine molecule interleukin-6 (IL-6) seems to promote tissue regeneration and block degeneration in a model of ...

The mechanism is based on the fact that the small molecule blocks the secretion of cytokines entirely. By inhibiting a target protein known as Sec61, ...

An inflammatory molecule called LIGHT, appears to be the cause of life-threatening airway damage in patients with severe asthma. According to the new research from scientists at La Jolla Institute ...