The DNA in our cells is constantly damaged, with the most severe being the simultaneous breakage of both strands that compose ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

ALKBH1 is a genomic DNA 6mA demethylase that preferentially removes 6mA in bubbled/bulged DNA and ssDNA, instead of dsDNA.

During DNA replication, the classic double helix can temporarily rearrange into an alternative structure known as a DNA three ...

Researchers at the University of Oxford and Nanyang Technological University, Singapore (NTU Singapore) have uncovered the ...

They include DNA restriction endonucleases (restriction enzymes) and their companion modification methylase restriction enzymes, DNA methyltransferases and related proteins, which are generally ...

A new drug was shown to significantly reduce tumor growth in lab studies by up to 77% for melanoma and colorectal cancers.

These findings highlight the dual roles of antioxidants in cancer. Their impact depends on cancer type, stage, and genetic alterations. In tumors where redox-sensitive signaling promotes cell death, ...