The structure of the genome can influence gene expression because active genes have to be physically accessible to the cell's transcription machinery. Chromatin contains loops that can connect parts ...

Whilst these tools can predict the overall structure, they often cannot look into smaller details, such as how transcription factors interact with each other on DNA.

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions.

Scientists discovered that ancient viral DNA sequences called MER11, once dismissed as genetic junk, actually act as ...

This review focuses on the unique characteristics of mitochondrial nucleoids in mammalian cells, highlighting their ...

Intrinsic termination relies on an RNA hairpin structure that forms in the RNA molecule being produced, ... (2021, May 7). New mechanism for terminating transcription of DNA into RNA in bacteria ...

The findings, captured within 500 milliseconds of RNAP mixing with DNA, shed light on fundamental mechanisms of transcription, and answer long-standing questions about the initiation mechanism and ...

Investigating DNA flexibility for the creation of new biomaterials. Northwestern investigators have demonstrated how manipulating DNA chemistry can alter its structure and flexibility and enable ...