Spacesmith authors share a few recommendations for bringing human-centered lighting to building design and construction.

Gain-of-function experiments are ingrained in the scientific process. In many instances, the benefits that stem from gain-of-function experiments are not immediately clear. Only decades later does the ...

Autosomal dominant optic atrophy (ADOA), the most common genetic optic neuropathy, is an insidious disease. It often presents ...

Parkinson's disease affects movement and more. It impacts mood, memory, and sleep. There is no cure, but diet helps manage ...

Active regional conductances and inhomogeneous distribution of membrane ionic channels in dendrites influence the integration of synaptic inputs in cortical neurons. How these properties shape the ...

At ARVO 2025, in Salt Lake City, Utah, Steven Barnes, PhD, talked about his research on the OPA1 mutation in retinal ganglion cells' effect on the cell's electrical function.

Nitric oxide is a type-selective neuromodulator affecting the temporal, but not the spatial response kinetics of a specific subset of mouse retinal ganglion cells.

We know that cells need ions like sodium and potassium to function—that’s why you need to drink not just water, but electrolytes when you run a marathon. Cells use these ions for many functions, like ...

A hyperreflective ganglion cell layer band on OCT can be found in approximately 25% of patients with retinitis pigmentosa and is associated with poor visual function.

Researchers induced non-neural cells that mimic ganglion cells in the eyes of mice, effectively reducing the impact of certain eye diseases. They hope to next replicate their technique in humans in ...

For the first time, non-neuronal cells have been induced to mimic specific ganglion cells in the eyes of mice.

Ala-Laurila explains that the ability to test the function of retinal cell-types specifically in starlight could also have clinical implications.