Researchers at the Francis Crick Institute have mapped the human metabolic pathways that Cryptosporidium, an intestinal parasite, requires to survive.

In a scientific first, researchers from Vanderbilt University and the University of California, San Diego, have generated a ...

In a typical undergraduate biochemistry course, two main educational objectives include (1) understanding and applying how genetic mutations can influence protein structure and function, and (2) ...

Large-scale metabolomic analyses of pan-cancer cell line panels have provided significant insights into the relationships between metabolism and cancer cell biology. Here, we took a pathway-centric ...

Microbial metabolic pathways to abrogate immunotherapy toxicity and promote anti-tumor response in metastatic renal cell cancer.

The pathway–pathway activation network was created based on the biochemical pathway definitions in the Yeast9 metabolic model (Data ref: Zhang et al, 2023). First, for each pair of pathways, the ...

The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.

Conclusions: Metabolic syndrome patients have elevated homocysteine levels, but these higher levels are not associated with an increased risk for new cardiovascular events. In contrast, elevated ...

Mechanistically, circ-PIAS1-5 activates the adenosine 5′-monophosphate (AMP)-activated protein kinase pathway by regulating TEAD1 through miR-219a-2-3p, and Hcy mediates the mA modification and ...