More information: Lipeng Mao et al, Human T cell development and aging: Remodeling throughout the lifespan, Aging Research (2024). DOI: 10.26599/AGR.2024.9340021 ...

Aging and secondary T cell development After their production in the thymus, newly produced T cells migrate into distinct sites within secondary lymphoid organs. Splenic T cells are found in the ...

Aging reduces CAR-T cell effectiveness by impairing metabolism, ... The authors call for age to be systematically considered in the development and evaluation of cell-based immunotherapies. Journal.

Researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell ...

In this work, published in the journal Nature Communications, the researchers have focused their study on how aging, a key risk factor that limits myelin regeneration, affects the regulatory T ...

To investigate the intrinsic role of aging on CD8 + T cell function, Prof. XIAO Yichuan's team from SINH and collaborators isolated CD8 + T cells from young and aged mice and then adoptively ...

Researchers have discovered that T cells in the body can be reprogrammed to slow down and even reverse aging. Using a mouse model, scientists found T cells can be used to fight off another type of ...