The robust Th1 bias observed in cellular responses, characterized by IFN-γ/IL-2 dominance and T-bet upregulation, with IgG1/IgG4 ratios > 1, is mechanistically associated with the aluminum hydroxide ...

Recent results from a cross-sectional study show that patients with immunoglobulin G4-related autoimmune pancreatitis (AIP) experience a high burden of disease-associated damage, iatrogenic injury ...

Careful evaluation of new therapies such as inebilizumab is essential in immunoglobulin G4-related disease (IgG4-RD), given the need to balance demonstrated efficacy with pharmacoeconomic realities ...

Patients with primary IgG4-related vasculitis exhibit higher levels of inflammatory markers, including total serum IgG, IgG1, IgG4, and C-reactive protein (CRP) (15).