CytomX Therapeutics, Inc. (Nasdaq: CTMX), a leader in the field of masked, conditionally activated biologics, today announced ...

GEN-1013, a non-replicating mRNA vector, delivers a dual payload - an enhanced prodrug-activated enzyme (HSV-eTK) and the immunostimulatory cytokine IL-12 – to achieve potent anti-tumor effects ...

The IL-12 cytokine factories in combination with checkpoint inhibitors successfully eliminated local and distal tumors in preclinical models of metastatic melanoma and colorectal and pancreatic ...

“IL-12 has shown promising anti-tumor activity, but its clinical use has been limited due to its inflammatory toxicity and narrow therapeutic window. By combining CytomX’s proprietary PROBODY ...

IL-12 is a powerful cytokine, a type of protein that acts as a chemical messenger, that plays a key role in initiating the body’s natural immune response. Several studies of IL-12 ...

NEW YORK -- Illinois is among a dozen states that sued the Trump administration in the U.S. Court of International Trade in New York on Wednesday to stop its tariff policy, saying it is unlawful ...

NEW YORK -- Illinois is among a dozen states that sued the Trump administration in the U.S. Court of International Trade in New York on Wednesday to stop its tariff policy, saying it is unlawful and ...