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Weekly 2.4 mg semaglutide was linked to improved liver histology results but did not significantly reduce body pain compared with placebo.

“In this study, NCA hit the primary and key secondary endpoint in this clinical trial that included liver histology and biochemical features,” said Trauner. “There were higher response rates ...

Naim Alkhouri, MD, spoke to the potential for glucagon-like peptide-1 (GLP-1) receptor agonists to transform the treatment landscape for patients with metabolic dysfunction-associated ...

Key Data Highlights: The composite MASHResInd score is a robust, non-invasive marker for liver histology improvement, with potential application across clinical research and practice.

FF-C1 improved liver histology in an additional mouse model fed a GAN diet, reinforcing the relevance of the CerS6–ceramide axis across experimental systems.

Nonalcoholic fatty liver disease (NAFLD) is an increasingly common condition that is believed to affect >25% of adults worldwide. Unless specific testing is done to identify NAFLD, the condition is ...

“Semaglutide met the criteria for regulatory approval by showing improvement in liver histology, which makes it reasonably likely that it will prevent cirrhosis and related outcomes.

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No liver abnormalities were recorded in these samples, and normal liver histology was confirmed when paraffin sections from the same resection were available. All control and FALD samples were ...

A 96-week clinical trial found that 300 mg of Vitamin E significantly improved liver histology and reduced inflammation in patients with MASH, with no major safety concerns reported.