News

The American Journal of Managed Care21h
FDA Approves First Treatment for KRAS-Mutated Recurrent LGSOC
FDA approves the first treatment for KRAS-mutated recurrent low-grade serous ovarian cancer (LGSOC), offering new hope for ...
EMBO Press3d
EGFR controls transcriptional and metabolic rewiring in KRAS G12D colorectal cancer
The role of EGFR in KRASG12D-driven tumorigenesis was studied using mouse CRC organoids with KRAS-APC-TP53 mutations and ...
eLife4d
Emergence of Dip2-mediated Specific DAG-based PKC Signalling Axis in Eukaryotes
(A) A model depicting the possible role of Dip2 in regulating DAG species required for PKC activation which governs the CWI pathway in yeast by activating the downstream MAPK cascade. Activation of ...
C&EN5d
Inhibition of Post-Surgical Tumor Recurrence by 3-Bromopyruvate-Conjugated Gold Nanoclusters via MAPK and PI3K-Akt Pathways
Shenzhen Key Laboratory of Smart Healthcare Engineering, Guangdong Provincial Key Laboratory of Advanced Biomaterials, Department of Biomedical Engineering, Southern University of Science and ...