Analyses of humanized FcRn mice are increasingly documenting their predictive value in modeling the PK behavior and efficacy of therapeutic hIgG mAbs in humans. The MHC class I-like molecule FcRn ...

GemPharmatech has developed a series of MHC-humanized mouse models to better evaluate the in vivo immunogenicity, efficacy and safety of mRNA vaccines, eliminating the inconsistencies in antigen ...

Eva Oswald is presenting on a PDX biobank in humanized mice and Steve Bronson is presenting on PMBC-humanized, MHC-deficient NCG mice that support human tumor xenographs without rapid onset GvHD ...

Given the interest in engaging these immune cell populations in cancer therapy, we established a new in vivo humanized mouse model through the adoptive transfer of human γδT cells to support this ...

Both soft (for example, epigenetic silencing and transcriptional downregulation), and hard (genetic mutations), loss of MHC I could lead to downregulation ... By leveraging multi-platform strategies, ...

DELRAY BEACH, Fla., April 22, 2025 /PRNewswire/ -- The global Humanized Mouse and Rat Model Market, valued at US$255.8 million in 2024, is forecasted to grow at a robust CAGR of 8.2%, reaching US$ ...