To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T ...

Complementary nature of these two immunotherapies leads to excellent 17.6-month median Overall Survival in head and neck cancer patients with PD-L1 CPS 1; Mature overall survival ...

Influenza viruses are among the most likely triggers of future pandemics. A research team from the Helmholtz Center for Infection Research (HZI) and the Medical Center—University of Freiburg has ...

Type 1 diabetes is an immune-mediated disease in ... including mice that have human islets, MHC molecules and TCRs? Little is understood about the function of macrophages, mast cells and various ...

A new class of molecules capable of killing the cancer cells that are refractory to standard treatments and responsible for recurrence has just been developed. This crucial advance in the fight ...

In a new study, researchers have identified a way to stop cells from dying, opening the door to developing treatments that ...

Current anticancer treatments essentially target the primary tumor cells that proliferate quickly, but do not effectively ...