The major histocompatibility complex class I (MHC-I) antigen presentation pathway is central to the adaptive immune response. In this process, intracellular proteins are degraded primarily by the ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating autophagy and MHC-I expression. The research, conducted by scientists from ...

The ability to use MHC class II proteins for cell entry could have been one of the reasons why H2N2 influenza viruses emerged as a pandemic virus in Asia back in 1957.

They use an alternative entry pathway,” says Stertz. The researchers found that hemagglutinin also binds to MHC class II protein complexes.

They use an alternative entry pathway," says Stertz. The researchers found that hemagglutinin also binds to MHC class II protein complexes.