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AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.
As described above, there is also evidence that the MAP-kinase pathway can affect BAD phosphorylation, although in this case the mechanism involved is unknown 14.
In this valuable study, the authors provide a simple yet elegant approach to identifying therapeutic targets that synergize to prevent therapeutic resistance in ovarian cancer using cell lines, ...