AMP-activated protein kinase (AMPK) plays a central role in maintaining energy balance in cells, especially under energy stress.

This study highlights novel genotype-driven metabolic adaptations in PM, laying the groundwork for targeted interventions ...

The field of obesity and metabolism in endocrine-related cancers is gaining significant attention due to the complex ...

The authors study how apolipoprotein L1 variants impact inflammation and lipid accumulation in macrophages. The findings will be useful for researchers investigating macrophage metabolism and ...

Emeli Chatterjee, Ph.D., of the Cardiovascular Research Center at Massachusetts General Hospital, is the lead author and ...

Absence of cysteine in mice coaxed fat-storing cells to burn energy, causing weight loss and offering potential therapeutic ...

Although archaea play a crucial role in the global biogeochemical cycle, our understanding of their metabolic diversity is still limited. Research into the metabolic pathways of archaea expands our ...

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth. It explores key amino acid pathways—including glutamine, serine, ...

Artificial humic acid enhances metabolic coupling between carbon fixation and methane production in paddy soils. This process links the Wood−Ljungdahl pathway and acetoclastic methanogenesis throug ...

MS/MS-based untargeted metabolomics generates complex data, but pathway enrichment analysis is constrained by the low annotation rates of metabolic features. Here, we propose MS2MP, a novel deep ...

However, its potential role in macrophage metabolic reprogramming, particularly in the context of hepatic glucose metabolism, has not been explored. In this study, we identify a novel mechanism by ...