Methotrexate injectable intravenous (IV) solution is only available as a generic drug. It doesn’t have a brand-name version. Methotrexate comes in four forms: injectable IV solution, self ...

The study suggests a potential benefit of routine multidose methotrexate treatment for recurrent cases of ectopic pregnancy.

January 17, 2012 — The US Food and Drug Administration (FDA) has approved glucarpidase (Voraxaze, BTG International Inc) as a treatment for the rapid and sustained reduction of toxic ...

One 5-mg reduction in the dose of methotrexate or its placebo was allowed for patients whose serum aminotransferase concentrations increased to at least 2.5 times the upper limit of the normal range.

The authors found that patients in the high methotrexate category had a significantly lower lumbar spine z score, a measure of BMD, compared with the low/intermediate group (–0.86 vs –0.14; P ...

For 204 of 236 patients, the lowest optimally efficient dose (LOED) could be calculated: 10 mg weekly was the most frequent LOED in the 104 patients receiving both methotrexate and prednisone ...

Methotrexate is a slow-acting disease-modifying antirheumatic drug (time to maximum therapeutic response is approximately 6 months), and delayed dose escalation might result in a loss of efficacy ...