Though misoprostol’s widespread availability—and its over-the-counter status in other countries—has long made it a popular choice for people managing their own abortions outside a clinical ...

While misoprostol-only abortions are very safe—an analysis of the protocol in the journal Contraception noted only up to 0.7% of patients in studies had complications requiring hospitalization ...

Although using misoprostol without mifepristone is off-label and not approved by the FDA, OB-GYNs and abortion rights advocates are saying that it is, in fact, a safe way to induce an abortion ...

Misoprostol can cause uterine cramping, nausea and vomiting. Some research suggests that patients are more likely to experience fever, chills and diarrhea than those who use the two-drug regimen.

"The combination of misoprostol and mifepristone is FDA-approved for medical abortions," the NIH website says. "In instances where mifepristone is unavailable, a misoprostol-only regimen is the ...

Misoprostol alone is considered a safe and effective way to have an abortion, studies show. It has been used that way for decades. The two drugs work differently. Mifepristone blocks a hormone ...

Misoprostol, marketed as Cytotec, is normally used in conjunction with the abortion pill mifepristone but can be used alone.

Misoprostol, one of the two drugs used in a medication abortion, is displayed at a clinic in Santa Teresa, New Mexico, on June 17, 2022. ROBYN BECK/AFP via Getty Images ...

Use of misoprostol alone was shown to be effective in self-managed abortion, with minimal side effects, according to a prospective observational cohort study of callers to safe abortion hotlines ...

Experts say misoprostol is safe and effective when used on its own. An imminent ruling from a Texas federal judge could soon block the use of a common abortion medication across the United States ...

Called "medicinal abortion" or "pill abortion," this method was first authorized by the Food and Drug Administration in 2000 when mifepristone, or RU-486, was approved for use up to the seventh ...