We have other oral medications that target a pathway called de novo lipogenesis, and they target lipid synthesis in the liver. And these medications might be coming before the end of this decade.

Honey contains compounds like flavonoids and phenolic acids, which are thought to enhance lipolysis (the breakdown of fat for fuel) and prevent lipogenesis (fat production). Helping you feel fuller.

Adrian J McNairn; Yanne Doucet; Julien Demaude; Marion Brusadelli; Christopher B Gordon; Armando Uribe-Rivera; Paul F Lambert; Charbel Bouez; Lionel Breton; Géraldine Guasch To determine the ...

Nonalcoholic fatty liver disease (NAFLD) can be reversed with several lifestyle changes, including diet and physical activity. NAFLD is a condition where fat builds up around the liver and is ...

Introduction: Hepatic de novo lipogenesis (DNL) is the biological process of fatty acids synthesis from non-lipid precursors of glycolysis. Elevated DNL has been implicated in metabolic dysregulation, ...

Obesity and Metabolism Laboratory, The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 9112001, Israel Laboratory of Nano Delivery ...

National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China Department of Radiology, Union ...

This important study shows that nutrient stress emanating from the microenvironment induces metabolic vulnerabilities in pancreatic ductal adenocarcinoma (PDAC). Using a combination of cell-based and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Global hepatic DNA methylation change has been ...

Background Injured or reactive biliary epithelial cells participate in most chronic liver injuries in a process referred to as ductular reaction, which involves multicellular interactions with marked ...